NFKB1 and infection: Infection with P. aeruginosa also induced significantly higher levels of nuclear p65-DNA binding (2 and 4 hours, p<0.001 and p<0.01, Fig 1B) and significantly higher nuclear p50-DNA binding in response to infection (at 4 hours, p<0.001, Fig 1C), but P. aeruginosa did not change nuclear RelB- or p52-DNA binding (Fig 1D and 1E).