CD4 and Cryptococcal meningitis: However, after adjusting for fungal burden, CSF HIV-1 VL, ART status and CD4+ T-cell count, this did not reach statistical significance (adjusted odds ratio (aOR) = 7.88, 95% confidence intervals (CI) = 0.75–83.4, P = .09) (See Table 1, Supplemental content 1, http://links.lww.com/MD/E974, which illustrates predictors of mental status in participants with HIV-associated Cryptococcal Meningitis).