In thyroid cancer, Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is upregulated in several subtypes such as papillary and follicular cancer [13] and Homeobox transcript antisense RNA (HOTAIR) acts as an oncogene and correlates with metastasis and poor prognosis [12]. The gene discussed is HOTAIR; the disease is thyroid cancer.