TLR4 and bacterial urinary tract infection: Specific impairment of UPEC‐UTI clearance in innate immune competent mice indicates that metabolic acidosis attenuates some aspect of Tlr‐4‐dependent innate immune defense that includes neutrophil recruitment and/or function (Chassin et al., 2006; Haraoka et al., 1999; Shahin et al., 1987).