CXCR2 and infection: Chemokines (CXCL 1, 2, and 5) induced by UPEC‐UTI concurrent with metabolic acidosis (Figure 4) are CXCR 2 ligands that play a prominent role in recruitment of neutrophils to sites of infection (Rajarathnam, Schnoor, Richardson, & Rajagopal, 2019; Svensson, Irjala, Svanborg, & Godaly, 2008).