APOE and Huntington disease: Treatment of HD in ApoE-deficient mice resulted in an apparent increase in the expression levels of LDL-R and LOX-1, which were almost reversed by rosuvastatin and/or sarpogrelate treatment (∗P < 0.05 vs. ApoE−/− HD; #P < 0.05 vs. ApoE−/− HD+R) (Figure 3(a)).