The mice from the ApoE−/− HD group exhibited increased expression levels of CD68, which was almost reversed by rosuvastatin and/or sarpogrelate treatment in mice from the ApoE−/− HD+R or ApoE−/− HD+R+S group (∗P < 0.05 vs. ApoE−/− HD) (Figure 2(b)). The gene discussed is APOE; the disease is Huntington disease.