de Almeida and other colleagues [14] analyzed the DNA methylation and gene expression data between breast cancer tissue and corresponding normal tissue in TCGA and found that cg12374721 (PRAC2), cg18081940 (TDRD10), and cg04475027 (TMEM132C) could be used as diagnostic and prognostic markers in breast cancer. The gene discussed is PRAC2; the disease is breast carcinoma.