Enhancement of the activities of some antioxidant enzymes such as catalase (CAT), glutathione reductase (GR), glutathione peroxidase (GPx), heme oxygenase 1 (HO-1), and superoxide dismutase (SOD) can inhibit oxidative stress and thereby delay the development of liver fibrosis [13]. This evidence concerns the gene HMOX1 and Hepatic fibrosis.