In addition, WFA inhibited the vimentin intermediate filament (VimIF) assembly and induced autophagy in the idiopathic pulmonary fibrosis fibroblast, and further demonstrated that WFA-induced VimIF disruption could increase collagen type I turnover in autophagosomes in IPF fibroblasts, and then exert its antifibrotic effects [43]. The gene discussed is VIM; the disease is pulmonary fibrosis.