Interestingly, WFA inhibited bile duct ligation-induced liver fibrosis in mice mainly by modulating extracellular matrix deposition, and it was further shown that lysyl oxidase like 2 (LOXL2), snail, vimentin, and NF-κB signaling were involved in the hepatoprotective effect of WFA against liver fibrosis [29]. The gene discussed is LOXL2; the disease is Hepatic fibrosis.