The 17 genes associated with PCa were mainly involved in cancer and prostate cancer-related pathways, which include the prostate cancer pathway, focal adhesion pathway, PI3K-Akt signaling pathway, regulation of actin cytoskeleton pathway, ECM-receptor interaction pathway, proteoglycans in cancer pathway, pathways in cancer, and AMPK signaling pathway. Here, AKT1 is linked to Familial prostate cancer.