It usually functioned as a ceRNA; for example, it could prevent miR-19a and miR-93 from interacting with their target mRNAs and elevate the expression levels of PTEN and PHLPP2 respectively, which inhibited PI3K/AKT/mTOR pathway and eventually suppressed the proliferation of glioma [89, 90]. The gene discussed is AKT1; the disease is central nervous system cancer.