Moreover, monoubiquitinated FANCD2 (ub-FANCD2) is required for FANCI monoubiquitination (ub-FANCI) and recruitment of Breast Cancer 1 (BRCA1), Fanconi Anemia Complementation Group J (FANCJ), and Fanconi Anemia Complementation Group N (FANCN), to form damage-induced foci on chromatin 29,30. The gene discussed is BRCA1; the disease is Fanconi anemia.