In the seven registered ovarian cancer cells (IGROV1, OVCAR-3, OVCAR-4, OVCAR-5, OVCAR-8, SKOV-3, and NCI/ADR-RES), the average transcript intensity z scores of miR-522-3p and E2F2 were inversely correlated (Spearman correlation = − 0.64, P = 0.1194, Fig. 4G), suggesting that miR-522-3p is among the key regulators of E2F2 in ovarian cancer cells. The gene discussed is E2F2; the disease is ovarian cancer.