For early prognosis purposes, the STAg/CC index for IL-5+CD4+ T-cells and IL-17A+CD4+ T-cells showed high performance (AUC > 0.8) to discriminate NL from L. Additionally, the STAg/CC index for IFN-γ+ NK-cells displayed high accuracy (AUC > 0.8) to discriminate AL from CL (Table 3). The gene discussed is IFNG; the disease is axial length measurement.