Notably, the royalblue1 (L2_Cux2_Lamp5) and darkorchid4 (L5–6_Fezf2_Tle4_Abo) modules, both similarly upregulated in epilepsy, shared nine genes including GRIK4 and GRIA1. The azure4 module (L4_Rorb_Schlap1_Met, upregulated in epilepsy) included the GRIK3 and GRM8 genes. The gene discussed is LAMP5; the disease is epilepsy.