SHISA9 and epilepsy: Notably, with respect to AMPA receptor auxiliary subunits, the darkorchid4 (L5–6_Fezf2_Tle4_Abo) and chocolate1 (L4_Rorb_Schlap1_Mme) modules, both upregulated in epilepsy, contained the SHISA9 gene (CKAMP44); the darkorchid4 module also included the CACNG3 gene (TARP-γ3), while the GSG1L gene was part of the royalblue1 (L2_Cux2_Lamp5), chocolate1 (L4_Rorb_Schlap1_Mme), and olivedrab2 (L5–6_Themis_Ntng2) modules (Source Data Table 15).