For instance, for Id2 neurons, the LAMP5-positive subfamily showed a larger epilepsy-related effect on their transcriptome than the LAMP5-negative subfamily (Fig. 2d), whereas for Vip neurons, Vip _Cbln1, Nrg1, Sema3c, and Tyr had a higher divergence of epileptic versus nonepileptic transcriptomes versus Vip_Abi3bp, Crh, and Sstr1, respectively. The gene discussed is TYR; the disease is epilepsy.