MTOR and esophageal squamous cell carcinoma: Dysregulation of mTOR signaling plays a crucial role in tumorigenesis, angiogenesis, cell growth, and metastasis.73 Elevated levels of p-mTOR are related to poor prognosis in ESCC, which lends itself as a therapeutic target for ESCC.74 Everolimus is an mTOR inhibitor with an excellent antitumor effect.