KLK3 and posterior cortical atrophy: The best cut-off value for PSAD and TZPSAD in predicting PCa in men with a PSA of 4.0–10.0 ng/ml were 0.174 ng/ml (sensitivity = 64.6% and specificity = 67.5%), and 0.367 ng/ml/ml (sensitivity = 50% and specificity = 77.5%), respectively.