Similarly, ITGA5, ITGA10, and ITGAE were overexpressed in FL B cells and FL-BM-MSC, whereas FL-Tfh up-regulated ITGAE. The expression of VCAM1 was similarly up-regulated in FL-derived B and stromal cells, while the expression of clusterin (CLU), in addition to its production by MSC, was up-regulated in tumor B cells. The gene discussed is ITGA5; the disease is neoplasm.