IL4 and escherichia coli infection: In addition, Bisson et al. [80] showed that a probiotic given to rats—containing L. helveticus R0052, B. longum R0175, Lacticaseibacillus rhamnosus R0011 and Saccharomyces boulardii yeasts—reduced pro-inflammatory analytes in serum (e.g., IL-1α, IL-6) and induced production of IL-4 and IL-10 after Escherichia coli infection.