Zhang et al. suggested that lncRNA HCG11 promotes the proliferation and migration of gastric cancer cells through miR-1276/CTNNB1 and the Wnt signaling pathway [36]; Chen et al. showed that lncRNA HCG11 inhibited glioma progression via regulating miR-496/CPEB3 axis and may be a potential therapeutic target [37]; Li et al. found that lncRNA HCG11 accelerates the proliferation and metastasis of hepatocellular carcinoma via miR-26a-5p/ATG12 axis [38]. This evidence concerns the gene HCG11 and central nervous system cancer.