In response to herpesvirus infection, TLR2 plays a role in inducing interferon γ in neurons and cytokines in peritoneal macrophages, as well as controlling viral load in the CNS (Kurt-Jones et al., 2004; Lima et al., 2010; Sørensen et al., 2008). The gene discussed is TLR2; the disease is Herpesviridae infectious disease.