Mathew Mathew R R Zeballos Zeballos G G Tun Tun H H Gewitz Gewitz M M Role of nitric oxide and endothelin-1 in monocrotaline-induced pulmonary hypertension in rats Role of nitric oxide and endothelin-1 in monocrotaline-induced pulmonary hypertension in rats Cardiovasc Res Cardiovasc Res 1995 1995 30 30 5 5 739 739 746 746 8595621 8595621. This evidence concerns the gene EDN1 and pulmonary hypertension.