Of note, molecular NF1 testing was performed in blood and tumor in two patients (patient 2: p.514_514del, and patient 18: p.888fs, both detected by gene panel sequencing) and only in blood in one patient (patient 4: p.1153fs detected by targeted sequencing of the NF1 gene including exon-flanking intronic regions). This evidence concerns the gene NF1 and neoplasm.