The obesity of the C57BL/6 mice, induced either by taking a HFD28, 32, 35, 36, 51, 52, 79 or by genetic alteration,13, 35 leads to a protumoral effect by increasing tumor growth,13, 28, 32, 52 promoting tumor angiogenesis,28, 32 having an immunomodulatory effect28 as well as activating pro‐tumor pathways such as AKT/mTOR.13 The gene discussed is AKT1; the disease is neoplasm.