Interestingly, whereas fibroblastic FAK inactivation does not impact lymphocyte T CD8+ number in the whole tumour (Fig EV3A and B and D left), it increases the number of these cytotoxic T lymphocytes specifically within the fibrotic area (but without decreasing their number in either the tumoural or adjacent areas; Fig EV3D). The gene discussed is CD8A; the disease is neoplasm.