On the contrary, treatment with ACE-I or angiotensin receptor blocker (ARB) and IL-6 levels were not significantly related to the development of AKI (HR 1.55 [95% CI 0.99–2.43], p = 0.057; HR 0.91 [95% CI 0.56–1.50], p = 0.705 and HR 1.00 [95% CI 1.00–1.00], p = 0.208, respectively). The gene discussed is IL6; the disease is acute kidney injury.