CHPT1 mediates metabolic changes in breast cancer cells, and silencing CHPT1 can inhibit breast cancer cell proliferation and early metastasis of tamoxifen-resistant breast cancer cells, suggesting that CHPT1 is a treatment target for cancers (Fedorova et al., 2019; Jia et al., 2016). The gene discussed is CHPT1; the disease is breast carcinoma.