The 10‐biomarker panel for age groups consisted of the blood immune/senescence markers: miR‐326, miR‐155, p16INK4a, IL‐17A, Gal‐9, IP‐10, IGF‐1 and naive CD8+CD27+CD28+ cells in combination with the tumor immune infiltrate markers: whole tumor density of CD8+ cells and tumor centre density of CD3+ cells. Here, CD28 is linked to neoplasm.