In a linear regression model adjusted for gender, age, BMI, eGFR, LVEF, ASE grade, 6-min walking test, and SF-36 physical functioning, we found that log-transformed galectin-3 concentrations independently predicted HADS anxiety (B = -2.493, 95%CI = -4.354–-0.632, p = 0.009) (Table 2, model 1). Here, LGALS3 is linked to Anxiety.