However, in our study, we found a much lower reduction in GPA for REST (0.50 ± 0.06) compared with ALL (0.52 ± 0.01) and MHC (0.55 ± 0.33), in contrast to in Serão et al. (2016), who reported a GPA of 0.12 for REST and 0.31 and 0.28 for ALL and MHC, respectively, when validating on crossbred animals. The gene discussed is HLA-C; the disease is acute lymphoblastic leukemia.