Ts (mouse TS) expression was quantified in morphologically and functionally distinct mesenchymal-like (Ladi 3.1) and epithelial-like (Ladi 2.1) cells (Supplementary Fig. 4A, B), isolated from the same mouse model of NSCLC (p53fl/fl-LSL KRASG12D/+). Here, TYMS is linked to non-small cell lung carcinoma.