REN and COVID-19: For medications, the proportion of those hospitalised with COVID-19 in the US who had been taking agents acting on the renin–angiotensin system over the 30 days up to their hospitalisation ranged from 18% to 39%, while the proportions taking immunosuppressants ranged from 4 to 6%, and from 21 to 51% for lipid-modifying agents over the same time period.