XIAP and rheumatoid arthritis: However, XIAP levels were significantly inhibited in HFLS-RA cells after transfection with miR-410-3p mimics (p = 0.0006 and p = 0.0001, respectively, Supplementary Fig 2 A-C), suggesting that miR-431-5p and miR-410-3p might exert similar effects in RA FLSs through overlapping mechanisms.