Meanwhile, the further analysis suggested that positive relationships between PCSK9 and several lipid-related markers including TC, LDL-C, non-HDL-C, apoA1 and apoB remained in DM group (r = 0.133, p = 0.010; r = 0.153, p = 0.003; r = 0.104, p = 0.043; r = 0.104, p = 0.044; r = 0.138, p = 0.007, respectively) and non-DM group (r = 0.234, p < 0.0001; r = 0.215, p < 0.0001; r = 0.217, p < 0.0001; r = 0.090, p = 0.009; r = 0.213, p < 0.0001, respectively). The gene discussed is APOB; the disease is diabetes mellitus.