NFATC1 and hepatocellular carcinoma: Due to the complex functions of NFAT2, the role of NFAT2 in HCC has not been clearly clarified and the existed research data displays completely opposite effect of NFAT2 in HCC [17, 18] Therefore, more research on the effect of NFAT2 in HCC is necessary for profoundly understanding the potential role of NFAT2 in HCC therapy.