NGFR and Duchenne muscular dystrophy: Lastly, in order to evaluate whether changes in the proNGF/p75NTR axis observed in mdx mice were also recapitulated in the muscles from DMD patients, we interrogated RNA-Seq data published by Khairallah and colleagues [48], and found that both ngf and p75NTR transcript levels significantly increased in DMD muscles when compared to control individuals (Figure 9E).