As shown in Table 2, no significant difference was observed for patients with prostate cancer among the rs1412125, rs2249825, rs1045411, and rs1360485 polymorphisms of the HMGB1 gene and those with the wild-type (WT) gene in the pre- and post-adjustment for age (Table 2). The gene discussed is HMGB1; the disease is prostate carcinoma.