Soon after iPSC-CMs became acceptable/attractive for modeling inherited heart diseases, several groups employed iPSC-CMs generated from LQTS patients carrying different disease-causing mutations such as KCNQ1 and KCNH2. Moretti et al. [87] generated iPSC-CMs from members of a family affected by LQTS type 1 caused by missense mutation in the KCNQ1 gene. This evidence concerns the gene KCNH2 and familial long QT syndrome.