In PR3-ANCA vasculitis, levels of TNF-α, thromboxane A2 (TXA2) and CD14 [117] were increased, while in MPO-ANCA vasculitis the C-C motif chemokine receptor 8 (CCR8) levels was higher and IL-10 expression was lower compared to controls. This evidence concerns the gene PRTN3 and vasculitis.