PRTN3 and vasculitis: Several lines of evidence coming from the genetic background of these diseases, the clinical disease course (association with relapses), disease manifestations (i.e., lung alterations), prognosis (i.e., cardiovascular death) and biomarker expression levels suggest that diagnosis should be made by the respective ANCA serotype, either PR3-ANCA vasculitis or MPO-ANCA vasculitis.