Binary regression analysis regarding obstetric risk factors revealed that fetal macrosomia, type of birth, time of birth, history of diabetes in a first degree relative, and insulin use in pregnancy had no significant effect on the development of MetS 10 years after delivery (Odds ratio; 95% CI and P values are: 0.483; 0.123–1.895, P = 0.297, 1.193; 0.450–3.162, P = 0.723, 1.202; 0.423–3.416, P = 0.730, 1.786; 0.504–6.335, P = 0.369, and 1.723; 0.592–5.018, P = 0.318, respectively). This evidence concerns the gene INS and diabetes mellitus.