We induced ecdRNAi for 48 h in the dorsal compartment of ubi‐AT1.03NL wing discs using apGalts and observed a drop in steady‐state levels of ATP in the dorsal ecdRNAi tissue (Fig 1L and M), mimicking the effect of glycolytic enzyme knock‐down in the wing (Fig 1G–K) and loss of Ecd in pancreatic cancer cells (Dey et al, 2012). Here, ECD is linked to familial pancreatic carcinoma.