To identify the mediator of TSP‐2‐promoted osteosarcoma migration, we examined levels of MMP‐1, MMP‐2, MMP‐3, MMP‐7, MMP‐9, MMP‐12 and MMP‐13 mRNA expression following TSP‐2 stimulation (Figure 2A,B). Here, MMP9 is linked to osteosarcoma.