DEP domain containing 1 (DEPDC1) is an oncogenic molecule, which plays an important role in various malignant tumours, including bladder cancer,6 hepatocellular carcinomas (HCC),7 prostate cancer8 and breast cancer,9 and may serve as prognostic predictor in HCC7 and breast cancer.10 The gene discussed is DEPDC1; the disease is urinary bladder cancer.