LRPAP1 and glioblastoma: However, only the association between genetically determined increased LTL and GBM risk (IVW-RE: ORSD = 4.86 (95% CI: 1.14–20.63, P = 3.23 × 10−2) and IVW-FE: ORSD = 4.86 (95% CI: 3.65–6.46, P = 1.80 × 10−27)) was consistent under WME, WMBE and MR-RAP models (Supplementary Table B4).