C6orf141 and Salla disease: Meanwhile, exons and gene levels of HERC4, EPHX2 and C6orf141 were confirmed to be highly expressed in IBC tissues, these three AS events were the first to be discovered in IBC, notably, the exon-level expression of HERC4 and EPHX2 is upregulated in the SD group, which corresponds with the findings that the skipping of these exons is a relative protective indexes.