A comparable glioma-associated signature was also observed in microglia 5 (cluster 6 (e.g., Ccl3, Apoe, and Lpl) Supplementary Fig. 8a, b), and within these two microglial clusters, we observed a similar enrichment of GO terms related to cytokine secretion107 and protein translation110 (Fig. 10d). The gene discussed is APOE; the disease is glioma.