When we further assessed if the increase in CD11b+ myeloid cells was the result of an increase in numbers of neutrophils and monocytes, we found no significant difference in the number of neutrophils present in IL-33+ glioma, however, there was a pronounced approximately four-fold increase in the number of inflammatory Ly6Chigh monocytes (Fig. 9). Here, ITGAM is linked to central nervous system cancer.