Fold-change in IL32 expression mirrored upregulation of proliferation marker Ki67, cell cycle regulator CDKN1A (p21CIP1/WAF1), metabolic reprogramming marker SLC2A1—encoding glucose transporter (GLUT1) angiogenic VEGFA, and IL7 and its receptor IL7Ra. Multivariate analysis, allowing for discerning associations independent from other covariates, showed a tight positive relationship between tumor IL32 expression and cell proliferation index and hypoxia, implying a tumor-promoting role for the interleukin. Here, MKI67 is linked to neoplasm.