TRAF2 and infection: While ECTV inhibited the IFN-γ + LPS-induced nuclear accumulation of p52 at 4 hpi, as well as expression of Nfkb2 gene and activation of both RelB and p52 at 18 hpi, we cannot exclude that the changes in the levels of cIAP1 and TRAF2 proteins induced by ECTV infection upon IFN-γ + LPS stimulation may facilitate apoptosis in ECTV-infected RAW 264.7 macrophages at later stages of infection.