On the other hand, MAGE-A expression profile of HCC reports that 92.3% of the tumors expressed one MAGE-A gene [111], while another study reported that MAGE/tetramer+ CD8 cells of patients with HCC are able to recognize the MAGE-1 sequence 161-169 and the MAGE-3 sequence 271-279 [112]. This evidence concerns the gene MAGEA3 and hepatocellular carcinoma.