PTBP1 and Granuloma: “Although progressive pulmonary tuberculosis, necrotic lesions, and an allergic state were easily demonstrated, other features commonly found in human pulmonary disease proved difficult to produce.” More recent publications report that sensitized rabbits can develop rapid onset exudative lesions reminiscent of PPTB and granulomas and cavities that develop from alveolitis in a fashion reminiscent to those of PPTB [131,132].