LSP1 and melanoma: As shown in online supplemental figure 5, no differences were found in the frequencies of CFSE-diluted cells or annexin V+ and/or PI+ cells in CD4+ and CD8+ T cells between the two groups of mice, suggesting that other mechanism(s) than cell proliferation and survival are responsible for the decrease of TILs in the melanoma of Lsp1 Tg mice.