INS and cardiovascular disorder: Type 2 diabetes mellitus (T2DM) is characterized by elevated blood glucose level that results from disturbances of insulin secretion and insulin action or both; it refers to a complex disorder impacted by both lifestyle and genetic factors.T2DM and its severe complications like nerve damages,[1] kidney diseases,[2] and cardiovascular diseases[3] have noticeably imposed societys medical burden over the past few decades.